Enantio and Diastereoselective Addition of Phenylacetylene to Racemic α-chloroketones
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چکیده
منابع مشابه
Enantio and diastereoselective addition of phenylacetylene to racemic α-chloroketones.
In this report, we have presented the first diastereoselective addition of phenylacetylene to chiral racemic chloroketones. The addition is controlled by the reactivity of the chloroketones that allowed the stereoselective reaction to be performed at -20 °C. Chiral racemic chloroketones are used in the reaction. By carefully controlling the temperature and the reaction time we were able to isol...
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ژورنال
عنوان ژورنال: Molecules
سال: 2011
ISSN: 1420-3049
DOI: 10.3390/molecules16065298